St. John's wort.
نویسنده
چکیده
منابع مشابه
A meta-analysis on the efficacy and safety of St John’s wort extract in depression therapy in comparison with selective serotonin reuptake inhibitors in adults
OBJECTIVE The aim of the study was to investigate the efficacy and safety of St John's wort extract and selective serotonin reuptake inhibitors (SSRIs) in the treatment of depression. METHODS Databases were searched for studies comparing efficacy and/or safety of St John's wort extract with SSRIs in depression from 1966 to April 2015. Stata software was used for statistical analysis. RESULT...
متن کاملFunctional induction and de-induction of P-glycoprotein by St. John's wort and its ingredients in a human colon adenocarcinoma cell line.
Continuous use of St. John's wort decreases the bioavailabilities of a variety of drugs. This interaction is attributed to the induction of cytochrome P450 3A4 and/or P-glycoprotein. In this study, we aimed to examine the chronic effects of St. John's wort and its constituents, hyperforin and hypericin, on the expression and function of P-glycoprotein in an intestinal cell line, LS 180. We also...
متن کاملSt. John's wort.
St. John's wort has been used to treat a variety of conditions. Several brands are standardized for content of hypericin and hyperforin, which are among the most researched active components of St. John's wort. St. John's wort has been found to be superior to placebo and equivalent to standard antidepressants for the treatment of mild to moderate depression. Studies of St. John's wort for the t...
متن کاملSt. John's Wort and Depression
St. John's Wort scientifically known as Hypericum Perforatum, an herbal remedy generally used to treat depression, is making a rise throughout Europe and the United States. St. John's Wort is a perennial plant that produces abundant yellow flowers and grows naturally throughout much of the world, including specifically in northern California, southern Oregon, and Colorado. It usually flowers on...
متن کاملSt John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties.
The chemical composition of St. John's wort has been well-studied. Documented pharmacological activities, including antidepressant, antiviral, and antibacterial effects, provide supporting evidence for several of the traditional uses stated for St John's wort. Many pharmacological activities appear to be attributable to hypericin and to the flavonoid constituents; hypericin is also reported to ...
متن کاملSt John's Wort supplements endanger the success of organ transplantation.
HYPOTHESIS St John's wort is one of the most popular herbal medicines, and health care professionals often are unaware that their patients take such supplements. St John's wort causes a decrease in cyclosporine levels, thus endangering the success of organ transplantations. DESIGN Systematic review. METHODS Five independent computerized literature searches were conducted to identify all rep...
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ورودعنوان ژورنال:
- The Journal of the Indiana State Medical Association
دوره 53 شماره
صفحات -
تاریخ انتشار 1960